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doxycycline dox chow  (Inotiv)
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Inotiv doxycycline dox chow
A. Experiment design. C57BL/6 mice were infected with ∼100 CFU of WT Erdman or ribA2 Tet-OFF by aerosol. At the indicated times (day 0, day 10 or week 6), groups mice were treated with <t>doxycycline</t> (dox; 2,000 ppm in chow), which was maintained for the duration of the experiment. Groups of mice ( n =6, 3M, 3F) were euthanized at the indicated time points to collect lungs and spleen. B-E. CFU enumeration in lung ( B, D ) and spleen ( C, E ) homogenates by serial dilution and plating on 7H10 agar (WT) or 7H10 with 53 μM riboflavin ( ribA2 Tet-OFF). Data are means ± SEM ( n =6). Blue “nd” indicates none detected for ribA2 Tet-OFF +dox d0. Asterisks indicate significant differences from the WT no dox control ( B, C ) or from the ribA2 Tet-OFF no dox control ( D, E ) by Welch’s t -test (24 hr and 1 wk lung data) or by one-way ANOVA with Dunnett’s multiple comparisons test post-hoc. * P <0.05, ** P <0.001.
Doxycycline Dox Chow, supplied by Inotiv, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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dox  (TargetMol)
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TargetMol dox
A. Experiment design. C57BL/6 mice were infected with ∼100 CFU of WT Erdman or ribA2 Tet-OFF by aerosol. At the indicated times (day 0, day 10 or week 6), groups mice were treated with <t>doxycycline</t> (dox; 2,000 ppm in chow), which was maintained for the duration of the experiment. Groups of mice ( n =6, 3M, 3F) were euthanized at the indicated time points to collect lungs and spleen. B-E. CFU enumeration in lung ( B, D ) and spleen ( C, E ) homogenates by serial dilution and plating on 7H10 agar (WT) or 7H10 with 53 μM riboflavin ( ribA2 Tet-OFF). Data are means ± SEM ( n =6). Blue “nd” indicates none detected for ribA2 Tet-OFF +dox d0. Asterisks indicate significant differences from the WT no dox control ( B, C ) or from the ribA2 Tet-OFF no dox control ( D, E ) by Welch’s t -test (24 hr and 1 wk lung data) or by one-way ANOVA with Dunnett’s multiple comparisons test post-hoc. * P <0.05, ** P <0.001.
Dox, supplied by TargetMol, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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doxycycline dox  (TargetMol)
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TargetMol doxycycline dox
A. Experiment design. C57BL/6 mice were infected with ∼100 CFU of WT Erdman or ribA2 Tet-OFF by aerosol. At the indicated times (day 0, day 10 or week 6), groups mice were treated with <t>doxycycline</t> (dox; 2,000 ppm in chow), which was maintained for the duration of the experiment. Groups of mice ( n =6, 3M, 3F) were euthanized at the indicated time points to collect lungs and spleen. B-E. CFU enumeration in lung ( B, D ) and spleen ( C, E ) homogenates by serial dilution and plating on 7H10 agar (WT) or 7H10 with 53 μM riboflavin ( ribA2 Tet-OFF). Data are means ± SEM ( n =6). Blue “nd” indicates none detected for ribA2 Tet-OFF +dox d0. Asterisks indicate significant differences from the WT no dox control ( B, C ) or from the ribA2 Tet-OFF no dox control ( D, E ) by Welch’s t -test (24 hr and 1 wk lung data) or by one-way ANOVA with Dunnett’s multiple comparisons test post-hoc. * P <0.05, ** P <0.001.
Doxycycline Dox, supplied by TargetMol, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dox+doxycycline/Doxycycline/pm42446805-116-115-118
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doxycycline dox - by Bioz Stars, 2026-11
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doxycycline dox  (Thermo Fisher)
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Thermo Fisher doxycycline dox
A. Experiment design. C57BL/6 mice were infected with ∼100 CFU of WT Erdman or ribA2 Tet-OFF by aerosol. At the indicated times (day 0, day 10 or week 6), groups mice were treated with <t>doxycycline</t> (dox; 2,000 ppm in chow), which was maintained for the duration of the experiment. Groups of mice ( n =6, 3M, 3F) were euthanized at the indicated time points to collect lungs and spleen. B-E. CFU enumeration in lung ( B, D ) and spleen ( C, E ) homogenates by serial dilution and plating on 7H10 agar (WT) or 7H10 with 53 μM riboflavin ( ribA2 Tet-OFF). Data are means ± SEM ( n =6). Blue “nd” indicates none detected for ribA2 Tet-OFF +dox d0. Asterisks indicate significant differences from the WT no dox control ( B, C ) or from the ribA2 Tet-OFF no dox control ( D, E ) by Welch’s t -test (24 hr and 1 wk lung data) or by one-way ANOVA with Dunnett’s multiple comparisons test post-hoc. * P <0.05, ** P <0.001.
Doxycycline Dox, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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dox  (MedChemExpress)
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MedChemExpress dox
A. Experiment design. C57BL/6 mice were infected with ∼100 CFU of WT Erdman or ribA2 Tet-OFF by aerosol. At the indicated times (day 0, day 10 or week 6), groups mice were treated with <t>doxycycline</t> (dox; 2,000 ppm in chow), which was maintained for the duration of the experiment. Groups of mice ( n =6, 3M, 3F) were euthanized at the indicated time points to collect lungs and spleen. B-E. CFU enumeration in lung ( B, D ) and spleen ( C, E ) homogenates by serial dilution and plating on 7H10 agar (WT) or 7H10 with 53 μM riboflavin ( ribA2 Tet-OFF). Data are means ± SEM ( n =6). Blue “nd” indicates none detected for ribA2 Tet-OFF +dox d0. Asterisks indicate significant differences from the WT no dox control ( B, C ) or from the ribA2 Tet-OFF no dox control ( D, E ) by Welch’s t -test (24 hr and 1 wk lung data) or by one-way ANOVA with Dunnett’s multiple comparisons test post-hoc. * P <0.05, ** P <0.001.
Dox, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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doxycycline dox inducible k562  (ATCC)
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A. Experiment design. C57BL/6 mice were infected with ∼100 CFU of WT Erdman or ribA2 Tet-OFF by aerosol. At the indicated times (day 0, day 10 or week 6), groups mice were treated with <t>doxycycline</t> (dox; 2,000 ppm in chow), which was maintained for the duration of the experiment. Groups of mice ( n =6, 3M, 3F) were euthanized at the indicated time points to collect lungs and spleen. B-E. CFU enumeration in lung ( B, D ) and spleen ( C, E ) homogenates by serial dilution and plating on 7H10 agar (WT) or 7H10 with 53 μM riboflavin ( ribA2 Tet-OFF). Data are means ± SEM ( n =6). Blue “nd” indicates none detected for ribA2 Tet-OFF +dox d0. Asterisks indicate significant differences from the WT no dox control ( B, C ) or from the ribA2 Tet-OFF no dox control ( D, E ) by Welch’s t -test (24 hr and 1 wk lung data) or by one-way ANOVA with Dunnett’s multiple comparisons test post-hoc. * P <0.05, ** P <0.001.
Doxycycline Dox Inducible K562, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dox+doxycycline/K-562/10__1158_slash_2643___3230__bcd___25___0446-212-55-59
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doxycycline dox  (MedChemExpress)
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MedChemExpress doxycycline dox
A. Experiment design. C57BL/6 mice were infected with ∼100 CFU of WT Erdman or ribA2 Tet-OFF by aerosol. At the indicated times (day 0, day 10 or week 6), groups mice were treated with <t>doxycycline</t> (dox; 2,000 ppm in chow), which was maintained for the duration of the experiment. Groups of mice ( n =6, 3M, 3F) were euthanized at the indicated time points to collect lungs and spleen. B-E. CFU enumeration in lung ( B, D ) and spleen ( C, E ) homogenates by serial dilution and plating on 7H10 agar (WT) or 7H10 with 53 μM riboflavin ( ribA2 Tet-OFF). Data are means ± SEM ( n =6). Blue “nd” indicates none detected for ribA2 Tet-OFF +dox d0. Asterisks indicate significant differences from the WT no dox control ( B, C ) or from the ribA2 Tet-OFF no dox control ( D, E ) by Welch’s t -test (24 hr and 1 wk lung data) or by one-way ANOVA with Dunnett’s multiple comparisons test post-hoc. * P <0.05, ** P <0.001.
Doxycycline Dox, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dox+doxycycline/Doxycycline/pm41910138-54-1-12
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doxycycline dox  (Shanghai Macklin Biochemical)
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Shanghai Macklin Biochemical doxycycline dox
A. Experiment design. C57BL/6 mice were infected with ∼100 CFU of WT Erdman or ribA2 Tet-OFF by aerosol. At the indicated times (day 0, day 10 or week 6), groups mice were treated with <t>doxycycline</t> (dox; 2,000 ppm in chow), which was maintained for the duration of the experiment. Groups of mice ( n =6, 3M, 3F) were euthanized at the indicated time points to collect lungs and spleen. B-E. CFU enumeration in lung ( B, D ) and spleen ( C, E ) homogenates by serial dilution and plating on 7H10 agar (WT) or 7H10 with 53 μM riboflavin ( ribA2 Tet-OFF). Data are means ± SEM ( n =6). Blue “nd” indicates none detected for ribA2 Tet-OFF +dox d0. Asterisks indicate significant differences from the WT no dox control ( B, C ) or from the ribA2 Tet-OFF no dox control ( D, E ) by Welch’s t -test (24 hr and 1 wk lung data) or by one-way ANOVA with Dunnett’s multiple comparisons test post-hoc. * P <0.05, ** P <0.001.
Doxycycline Dox, supplied by Shanghai Macklin Biochemical, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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dox  (Tocris)
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Tocris dox
A. Experiment design. C57BL/6 mice were infected with ∼100 CFU of WT Erdman or ribA2 Tet-OFF by aerosol. At the indicated times (day 0, day 10 or week 6), groups mice were treated with <t>doxycycline</t> (dox; 2,000 ppm in chow), which was maintained for the duration of the experiment. Groups of mice ( n =6, 3M, 3F) were euthanized at the indicated time points to collect lungs and spleen. B-E. CFU enumeration in lung ( B, D ) and spleen ( C, E ) homogenates by serial dilution and plating on 7H10 agar (WT) or 7H10 with 53 μM riboflavin ( ribA2 Tet-OFF). Data are means ± SEM ( n =6). Blue “nd” indicates none detected for ribA2 Tet-OFF +dox d0. Asterisks indicate significant differences from the WT no dox control ( B, C ) or from the ribA2 Tet-OFF no dox control ( D, E ) by Welch’s t -test (24 hr and 1 wk lung data) or by one-way ANOVA with Dunnett’s multiple comparisons test post-hoc. * P <0.05, ** P <0.001.
Dox, supplied by Tocris, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/dox+doxycycline/Doxycycline+hyclate/pmc12985393-197-80-81
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A. Experiment design. C57BL/6 mice were infected with ∼100 CFU of WT Erdman or ribA2 Tet-OFF by aerosol. At the indicated times (day 0, day 10 or week 6), groups mice were treated with doxycycline (dox; 2,000 ppm in chow), which was maintained for the duration of the experiment. Groups of mice ( n =6, 3M, 3F) were euthanized at the indicated time points to collect lungs and spleen. B-E. CFU enumeration in lung ( B, D ) and spleen ( C, E ) homogenates by serial dilution and plating on 7H10 agar (WT) or 7H10 with 53 μM riboflavin ( ribA2 Tet-OFF). Data are means ± SEM ( n =6). Blue “nd” indicates none detected for ribA2 Tet-OFF +dox d0. Asterisks indicate significant differences from the WT no dox control ( B, C ) or from the ribA2 Tet-OFF no dox control ( D, E ) by Welch’s t -test (24 hr and 1 wk lung data) or by one-way ANOVA with Dunnett’s multiple comparisons test post-hoc. * P <0.05, ** P <0.001.

Journal: bioRxiv

Article Title: Mycobacterium tuberculosis requires riboflavin biosynthesis for survival in the host

doi: 10.64898/2026.09.25.754416

Figure Lengend Snippet: A. Experiment design. C57BL/6 mice were infected with ∼100 CFU of WT Erdman or ribA2 Tet-OFF by aerosol. At the indicated times (day 0, day 10 or week 6), groups mice were treated with doxycycline (dox; 2,000 ppm in chow), which was maintained for the duration of the experiment. Groups of mice ( n =6, 3M, 3F) were euthanized at the indicated time points to collect lungs and spleen. B-E. CFU enumeration in lung ( B, D ) and spleen ( C, E ) homogenates by serial dilution and plating on 7H10 agar (WT) or 7H10 with 53 μM riboflavin ( ribA2 Tet-OFF). Data are means ± SEM ( n =6). Blue “nd” indicates none detected for ribA2 Tet-OFF +dox d0. Asterisks indicate significant differences from the WT no dox control ( B, C ) or from the ribA2 Tet-OFF no dox control ( D, E ) by Welch’s t -test (24 hr and 1 wk lung data) or by one-way ANOVA with Dunnett’s multiple comparisons test post-hoc. * P <0.05, ** P <0.001.

Article Snippet: Groups of mice were treated with doxycycline (dox) chow (Teklad Global 2018 diet containing 2,000 ppm dox; Envigo) starting at the following times: day 0 (immediately after infection), day 10 or day 42 (week 6) for C57BL/6 mice; day 21 (week 3) or day 42 (week 6) for C3HeB/FeJ mice.

Techniques: Infection, Aerosol, Serial Dilution, Control